Rana

 

Dr. P. Ranasinghe

Research Fellow

Herbal Technology Section

 

Qualifications                           

PhD, M. Phil,  B.Sc (Agric)

Contacts

Tel:  0714434767                  Email:This email address is being protected from spambots. You need JavaScript enabled to view it.                                            

Specialized Fields

Natural Product Biochemistry, Bioassay and cell culture

Plant Tissue culture

               Technology Commercialization

Interest Areas      

  • Pharmaceutical Biochemistry of functional natural products
  • Enzyme and Cell based bioassays
  • Technology commercialization and startup
  • Alcoholic beverage fermentation and palm sap

Publication

 

  1. Kodikara, K.A.S., J. Lokupulukkutuge, P. Ranasinghe, M. Kanishka, F. Dahdouh-Guebas, and N. Koedam, “Stress-induced carbon starvation in Rhizophora mucronata Lam. seedlings under conditions of prolonged submergence and water deficiency: Survive or succumb, Botanica Serbica, vol. 44, no. 2, pp. 149–162, 2020. https://doi.org/10.2298/BOTSERB2001011S
  2. Pathiranage, H. W. T., Weeratunge, H. D., N. M. Mubarak,   Godakumbura, P. I., & Ranasinghe, P. (2020). In Vitro Antioxidant and Antidiabetic Potentials of Syzygium caryophyllatum L . Alston, 2020. Evidence-Based Complementary and Alternative Medicine, 2020, 1–15. https://doi.org/https://doi.org/10.1155/2020/9529042
  3. Kodikara, K. A. S., Ranasinghe, P., Irfan, A., Loku Pullukuttige, J., Madarasinghe, S. K., Farid, D. G., & Nico, K. (2020). Oxidative stress, leaf photosynthetic capacity and dry matter content in young mangrove plant Rhizophora mucronata Lam. under prolonged submergence and soil water stress. Physiology and Molecular Biology of Plantshttps://doi.org/10.1007/s12298-020-00843-w
  4. Gunathilaka, T. L., Samarakoon, K., Ranasinghe, P., & Peiris, L. D. C. (2020). Review Article Antidiabetic Potential of Marine Brown Algae - a Mini Review, Journal of Diabetes Research, 2020. https://doi.org/10.1155/2020/1230218.
  5. Gunathilaka, T. L., Samarakoon, K. W., Ranasinghe, P., & Peiris, L. D. C. (2019). In-Vitro Antioxidant, Hypoglycemic Activity, and Identification of Bioactive Compounds in Phenol-Rich Extract from the Marine Red Algae Gracilaria edulis (Gmelin) Silva. Molecules (Basel, Switzerland), 24(20), 1–16. https://doi.org/10.3390/molecules 24203708.
  6. Gunawardena, H., Silva, R., & Ranasinghe, P. (2019). Human plasma dynamically quenches the fluorescein at the initial point of oxygen radical absorption capacity (ORAC) assay. BMC Research Notes, 12(1), 809. https://doi.org/10.1186/s13104-019-4845-4
  7. Gunawardena, H. P., Silva, R., Sivakanesan, R., Ranasinghe, P., & Katulanda, P. (2019). Poor Glycaemic Control Is Associated with Increased Lipid Peroxidation and Glutathione Peroxidase Activity in Type 2 Diabetes Patients. Oxidative Medicine and Cellular Longevity2019, 1–10. https://doi.org/10.1155/2019/9471697.
  8. Dharmadasa, R. M., Lintha, A., Wijesekara, R. G. S., Abeysinhe, D. C., & Ranasinghe, P. (2019). Use of Halosarcia indica (Willd.) Paul G. Wilson Extracts for Low Salted Dried Fish Production. World Journal of Agricultural Research, 7(4), 132–136. https://doi.org/10.12691/wjar-7-4-3
  9. Kathirgamanathar, S., Abeysekera, W. P. K. M., Weerasinghe, D. M. K. P., Ranasingha,P., & Binduhewa, A. M. C. U. (2018). Antioxidant, anti-amylase and lipid lowering potential of leaves of Aporosa Indleyana Baill. (Kebella). Sri Lanka Journal Of Biology3(1), 1.
  10. Shanura Fernando, I. P., Asanka Sanjeewa, K. K., Samarakoon, K. W., Lee, W. W., Kim, H.-S., Ranasingha, P., Gunasekara, U. K. D. S.S. & Jeon, Y.-J. (2018). Antioxidant and anti-inflammatory functionality of ten Sri Lankan seaweed extracts obtained by carbohydrase assisted extraction. Food Science and biotechnology. 1-9.
  11. Shanura Fernando, I. P., Asanka Sanjeewa, K. K., Samarakoon, K. W., Lee, W. W., Kim, H.-S., Kim, E-A., Ranasingha, P., Gunasekara, U. K. D. S.S. Premakumara G. A. S. & Jeon, Y.-J. (2018). Preliminary screening of two marine algae and sea grass harvested from Sri Lankan waters against the LPS-induced inflammatory responses in RAW 264.7 macrophages and in vitro zebrafish embryo model. Journal of National Science Foundation of Sri Lanka, 46(2): 117-124.
  12. Abeysekera, W.K.S.M.1., Jayawardana, S.A.S.1,, Abeysekera, W.P.K.M., Yathursan, S., Premakumara, G.A.S. and Ranasinghe, P. (2017). Antioxiant potential of selected whole grain cereals consumed by Sri Lankan: A comparative in vitro Sri Lanka Journal of Biology, 2 (2): 12-24.
  13. Fernando IPS, Sanjeewa KKA, Samarakoon KW, Lee WW, Kim HS, Kang N, Ranasinghe P, Lee HS, Jeon YJ. (2017). A fucoidan fraction purified from Chnoospora minima; a potential inhibitor of LPS-induced inflammatory responses. International Journal of Biological Macromolecules 104, 1185–1193
  14. Fonseka SI, Adikari S, Jayasekera LR, Ranasinghe P, Premakumara GAS. (2017). Seed germination inhibitory effectCaryota urens L. seed pericarp on rice and associated weeds. Tropical Plant Research, 4, 2349–9265.
  15. Wimalasiri, G. E. M., Ranasinghe, P., Gunaratne, D.M.A.L.P. Vidhana Arachchi (2016). Antioxidant and anti-diabetic properties of Caryota urens (Kithul) flour. Procedia Food Science   6: 181 – 185
  16. Weerasekera, K.R., Ranasinghe, P., Dhammarathana, I., Tissera, M.H.A. and Ariyawansha, H.A.S. (2013). Investigation of antioxidant activity of an Ayurvedic formulation Chandraprabha Vati. Sri Lankan Journal of Indigenous Medicine, 3 (2), 187-190.
  17. Ranasinghe, P., Ranasinghe, P., Abeysekera, W.P.K.M., Premakumara, G.A.S., Perera Y.S., Gurugama, P., and Gunatilake, S.B., (2012). In vitro erythrocyte membrane stabilization properties of Carica papaya L. leaf extracts, Pharmacognosy Research, 4 (4), 196-202.
  18. Ranasinghe, P., Premakumara, G.A.S., Wijayaratne, C.D. and Ratnasooriya, W.D. (2011). Antioxidant activity of Caryota urens (L.) sap. Tropical Agricultural Research, 23 (2), 117-125.
  19. Ranasinghe, P. and Ide, T. (2006). Dietary fish oil and sesamin synergistically increased hepatic fatty acid oxidation in Zucker rats. In Herbal medicine phytopharmaceuticals and other natural products: Trends and Advances. Arambewela, L.S.R., Wimalasena, S. and Gunawardana, N. (Eds.) Jointly published by the Centre for the Science and Technology of the Non-aligned and Other Developing Countries, New Delhi India and Institute of Chemistry, Sri Lanka. Page 389-394.
  20. Ide, T., Hong, D.D., Ranasinghe, P., Takahashi, Y., Kushiro, M. and Sugan. (2004). Interaction of dietary fat types and sesamin on hepatic fatty acid oxidation in rats. Molecular and Cell Biology of Lipids, Biochimica et Biophysica Acta. 1682 (1-3), 80-91.
  21. Yapabandara, Y.M.H.B. and Ranasinghe, P. (2000). Tissue culture for mass production of aquatic plant species. Asia Pacific Tech. Monitor, 17(6), 49-55

Patents

 

  1. Evaluation of natural product/medicinal plant extracts for their glucose and lipid metabolism in 3T3 L1 cell lines
  2. Commercialization of caned kithul toddy as sparking kithul ra
  3. Evaluation of extraction methods for purification of lignified kithul fiber from Kithul leaf and leaf-sheaths and evaluation of application potentials
  4. Chemometric fingerprinting of natural and adulterated toddy types
  5. Studies on functional properties and active principals of underutilized wild fruits and marine algea

 

 

 

 

Last Updated on Tuesday, 09 August 2022 11:26

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