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Dr. P. RANASINGHE

Senior Deputy Director
Herbal Technology Section

 

 

 

 

Qualifications

PhD. Bio Chemistry Molecular Biology - University of Colombo- 2013

M. Phil. (Plant Tissue Culture)- University of Colombo - 2003

B.Sc. (Agric) Agricultural Biotechnology – University of Peradeniya - 1997

Contacts

Tel: 94 012797323         E mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Specialized Fields

  • Natural Product Biochemistry
  • In vitro bioassay (antioxidant, glycation, enzyme)
  • Animal model experiments (Rat and mouse)
  • Molecular biology identification of yeast and fungi
  • Palm (Kithul, Coconut and Palmyrah) tapping and processing for natural sweeteners
  • Plant tissue and cell culture

Interest Areas       

  • Investigation on bioactive properties of traditional foods, wild fruits, marine algae and medicinal plants.
  • Interaction of functional properties of polyherbal medicines
  • Encapsulation of bioactive constituents in polyherbal mixtures
  • Enzyme assisted extraction of bioactive compounds from natural products /traditional medicinal mixtures.

Ongoing Research Projects

 

 

 

  • Investigation on bioactive properties of underutilized wild fruits in Sri Lanka and potential application in nutraceuticals.
  • Studies on bioactive properties of selected Sri Lankan Marine algae and their uses in nutraceutical and cosmetic products.
  • Standardization/Authentication of         herbs and polyherbal products using spectroscopic techniques.

Research Experience

  • Three years of working experience as a research student in project “Development of tissue culture protocols for mass production of endemic aquatic ornamental plants in Sri Lanka, from 1998 to 2000, funded by Council for Agriculture Research and Policy (CARP).
  • One year working experience in the field of functional food biotechnology at National Food Research Institute (NFRI), Tsukuba, Japan, Under COSTED/JICA programme from 2001 to 2002.
  • Maintained the plant tissue culture lab at ITI from 2003 to 2008.
  • A Co-investigator of the project “Upliftment of Kithul industry to meet challenges at local and export market' from   2003 to 2004, funded by Ministry of Rural Industries.
  • A co-investigator of the project “Development of non-chemical Kithul sap preservation methodology” from 2005 to 2006 funded by Ministry of Rural industries.
  • A co-investigator of the project 'Study on bioactivity of Kithul sap and treacle and molecular characterization of economically useful wild yeasts' from 2007 to 2010, funded under treasury grants.
  • Principal investigator of the project “Development of Bioactive Kithul Drink” from 2012 to 2014 funded under treasury grants.
  • A co-investigator of IPSAT project on “Establishment of proteomic facilities at ITI for drug leads discovery” from 2012 to 2014 funded by NSF.

Publication

  1. .Abeysekera, W.K.S.M.1., Jayawardana, S.A.S.1,, Abeysekera, W.P.K.M., Yathursan, S., Premakumara, G.A.S. and Ranasinghe, P. (2017). Antioxiant potential of selected whole grain cereals consumed by Sri Lankan : A comparative in vitroSri Lankan Journal of Biology, 2 (2): 12-24.
  2. Fernando IPS, Sanjeewa KKA, Samarakoon KW, Lee WW, Kim HS, Kang N, Ranasinghe P, Lee HS, Jeon YJ. (2017). A fucoidan fraction purified from Chnoospora minima; a potential inhibitor of LPS-induced inflammatory responses. International Journal of Biological Macromolecules 104, 1185–1193.
  3. Fonseka SI, Adikari S, Jayasekera LR, Ranasinghe P, Premakumara GAS. (2017). Seed germination inhibitory effect of Caryota urens L. seed pericarp on rice and associated weeds. Tropical Plant Research, 4, 2349–9265.
  4. Wimalasiri, G. E. M., Ranasinghe, P., Gunaratne,   D.M.A. and L.P. Vidhana Arachchi (2016). Antioxidant and anti-diabetic properties of Caryota urens (Kithul) flour. Procedia Food Science   6: 181 – 185.
  5. Weerasekera, K.R., Ranasinghe, P., Dhammarathana, I., Tissera, M.H.A. and Ariyawansha, H.A.S. (2013). Investigation of antioxidant activity of an ayurvedic formulation Chandraprabha Vati. Sri Lankan Journal of Indigenous Medicine, 3 (2), 187-190.
  6. Ranasinghe, P., Ranasinghe, P., Abeysekera, W.P.K.M., Premakumara, G.A.S., Perera Y.S., Gurugama, P., and Gunatilake, S.B., (2012). In vitro erythrocyte membrane stabilization properties of Carica papaya L. leaf extracts, Pharmacognosy Research, 4 (4), 196-202.
  7. Ranasinghe, P., Premakumara, G.A.S., Wijayaratne, C.D. and Ratnasooriya, W.D. (2011). Antioxidant activity of Caryota urens (L.) sap. Tropical Agricultural Research, 23 (2), 117-125.
  8. Ranasinghe, P., Ranasinghe, P., Abeysekera, W.P.K.M., Premakumara, G.A.S., Perera Y.S., Gurugama, P., Gunatilake, S.B., (2012). In vitro erythrocyte membrane stabilization properties of Carica papaya L. leaf extracts, Pharmacognosy Research, 4:4, 196-202.
  9. Ranasinghe, P., Premakumara, G.A.S., Wijayaratne, C.D. and Ratnasooriya, W.D. (2011). Antioxidant Activity of Caryota urens (L.) sap. Tropical Agricultural Research 23: (2), 117-125.
  10. Ranasinghe, P. and Ide, T. (2006). Dietary fish oil and sesamin synergistically increased hepatic fatty acid oxidation in Zucker rats, In Herbal Medicine Phytopharmaceuticals and other natural products: Trends and Advances, Eds, by Arambewela, L.S.R., Wimalasena,S. And Gunawardana, N. Jointly published by Centre for the Science and Technology of the Non-aligned and Other Developing Countries, New Delhi India and Institute of Chemistry, Ceylon, Sri Lanka. Page 389-394.
  11. Ide, T., Hong, D. D., Ranasinghe, P., Takahashi, Y., Kushiro, M. and Sugan. (2004). Interaction of dietary fat types and sesamin on hepatic fatty acid oxidation in rats. Molecular and Cell Biology of Lipids, Biochimica et Biophysica Acta. 1682: (1-3) 80-91.
  12. Yapabandara, Y. M. H. B. and Ranasinghe, P. (2000). Tissue culture for mass production of aquatic plant species. Asia Pacific Tech. Monitor 17: 6 49-55.

Patents

A new Kithul activation and sap production enhancing reagent (KASPER) as a ready to use treatment mixture for Kithul (Toddy palm) tapping (Patent No-13759).

 

 

 

 

Last Updated on Wednesday, 04 July 2018 13:25

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