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Dr. (Mrs). L. D. A. M. ARAWWAWALA

 

Senior Research Scientist


Herbal Technology Section

Qualifications

 

B.Sc. Hons. Biological Sciences

(University of Peradeniya- 2000)

 

M.Sc.  Food Science & Technology

(University of Sri Jayawardenapura, 2005)

 

M.Phil. Molecular Biology & Bio-Chemistry

(University of Peradeniya, 2006)

 

Ph.D. Bio-Chemistry

(University of Kelaniya, 2009)

 

Contacts

Tel: 94 011 2379848 ;       Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Specialized Fields

  • Bioactivity of natural products
  • Herbal drugs standardization
  • Functional foods and pharmaceuticals

Interest Areas       

  • Assessing functionality of foods and natural products
  • Development of functional foods and nutraceuticals

Publications

 

 

 

Journal Publications

  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Ratnasooriya, W.D., (2003). Safety evaluation of Sri Lankan Piper betle leaf extracts in rats. Journal of Tropical Medicinal Plants. 4, 195 – 198.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Ratnasooriya, W.D., (2004). Antinociceptive activities of aqueous and etahnolic extracts of Alpinia calcarata  rhizomes in rats. Journal of Ethnopharmacology 95, 311 - 316.
  • Arambewela, L.S.R., Kumarathunga, A., Arawwawala, M., Owen, N.L., Du, L., (2005). Volatile oils of Alpinia calcarata grown in Sri Lanka. Journal of Essential Oil Research  17, 124 - 125.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M. (2005). Antioxidant activities of ethanolic and hot aqueous extracts of Alpinia calcarata rhizomes. Australian Journal of Medical Herbalism 17, 91 - 94 .
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Ratnasooriya, W.D., (2005). Antidiabetic activities of  aqueous and ethanolic extracts of Piper betle leaves in rats. Journal of Ethnopharmacology 102, 239 – 245.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Ratnasooriya, W.D., (2005). Gastroprotective activity of hot ethanolic extract of Alpinia calcarata rhizomes in rats. Ceylon Journal of Medical Sciences 48, 1 – 11.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Ratnasooriya, W.D. (2005). Antinociceptive activity of  aqueous and ethanolic extracts of Piper betle leaves. Pharmaceutical Biology. 43, 766 -772.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Rajapaksa, R. (2006). Piper betle: A potential natural antioxidant. International Journal of Food Science and Technology. 41, 10 -14.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Dissanayake, D.C.T.R., Ratnasooriya, W.D. (2006). Bioactivities of betel leaves. Link Natural Product Digest 2, 25 – 26.
  • Arambewela, L.S.R., Kumarathunga, A., Arawwawala, M., Owen, N.L., Du, L. (2005)  Volatile oil of Alpinia galanga of Sri Lanka. Journal of Essential Oil Research 19, 455 – 456.
  • Wardhana, A., Kumarasinghe, S.P.W., Arawwawala, L.D.A.M., Arambewela, L.S.R. (2007). Larvicidal efficacy of essential oil of betel leaf (Piper betle) on the larvae of the old world screwworm fly, Chrysomya bezziana in vitro. Indian Journal of Dermatology. 52, 43 – 47.
  • Arawwawala, M., Thabrew, I., Arambewela, L.S.R. (2009). Antidiabetic activity of Trichosanthes cucumerina in normal and streptozotocin – induced diabetic rats. International Journal of Biology & Chemical Sciences. 2, 287 – 296.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Ratnasooriya, W.D. (2009). Effect of Alpinia calcarata rhizomes on ethanol – induced gastric ulcers in rats. Pharmacognosy Magazine. 4, 226 – 231.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Ratnasooriya, W.D. (2009). Hypoglycemic and antihyperglycemic activities of the aqueous and the ethanolic extracts of Alpinia calcarata rhizomes in rats. Pharmacognosy Magazine. 5, 412 – 418.
  • Arawwawala, L.D.A.M., Thabrew, I., Arambewela, L.S.R. (2010). Gastroprotective activity of Trichosanthes cucumerina in rats. Journal of Ethnopharmacology. 127, 750 – 754.
  • Arawwawala, L.D.A.M., Thabrew, I., Arambewela, L.S.R., Handunnetti, S. (2010). Antiinflammatory activity of Trichosanthes cucumerina in rats. Journal of Ethnopharmacology. 131, 538 – 543.
  • Arawwawala, L.D.A.M.,  Arambewela, L.S.R. (2010). Standardization of Alpinia calcarata Roscoe rhizomes. Pharmacognosy Research. 2, 285 – 288.
  • Arawwawala, L.D.A.M.,  Arambewela, L.S.R., Athauda, N. (2010).Antifungal and antioxidant properties of essential oil of Alpinia calcarata rhizomes. Journal of Ayurveda and Integrative Medicine. 1, 199-202.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Withanage, D., Kulathunga, S. (2010). Efficacy of betel cream on skin ailments. Journal of Complementary and Integrative Medicine, 7, Article 48.
  • Arawwawala, L.D.A.M.,  Hewageegana, H.G.S.P., Arambewela, L.S.R., Ariyawansa, H.S.  (2011). Standardization of spray dried powder of Piper betle hot water extract. Pharmacognosy Magazine. 7, 157–160.
  • Arawwawala, L.D.A.M., Thabrew, I., Arambewela, L.S.R. (2011). Evaluation of toxic potential of standardized aqueous and ethanolic extracts of Trichosanthes cucumerina in rats. BLACPMA. 1, 11-22.
  • Arawwawala, L.D.A.M., Thabrew, I., Arambewela, L.S.R. (2011). In vitro and in vivo evaluation of antioxidant activity of Trichosanthes cucumerina aerial parts. Acta Biologica Hungarica.62, 235 – 243.
  • Arambewela, L., Arawwawala, M., Ratnasooriya, W.D. Safety profile of Alpinia calcarata Roscoe, used in traditional medicine in Sri Lanka. BLACPMA. 10, 435 – 442.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Withanage, D., Kulathunga, S. (2011). Efficacy of betel cream on skin ailments with special reference of Vicharchika. Ayurveda Sameeksha. 2, 173 – 178.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Kumaratunga, K.G.A., Dissanayake, D.S.C.T., Ratnasooriya, W.D., Kumarasingha, S.P.W. (2011). Piper betle : A green healer from the backyard. Link Natural Products Digest. 16 -20.
  • Arawwawala, L.D.A.M., Thabrew, I., Arambewela, L.S.R., Fernando, N., Guruge, L.D (2011). Antibacterial activity of Trichosanthes cucumerina Linn extracts. International Journal of Pharmaceutical and Biological Archives. 2, 808 – 812.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Kumaratunga, K.G.A., Dissanayake, D.S.C.T., Ratnasooriya, W.D., Kumarasingha, S.P.W. (2011). Investigation on Piper betle grown in Sri Lanka. Pharmacognosy Review. 5, 159 – 163.
  • Hewageegana, H.G.S.P., Arawwawala, L.D.A.M., Arambewela, L.S.R., Ariyawansa, H.S. (2011). Piper betle: As a remedy for Diabetes Mellitus. International Journal of Research in Ayurveda and Pharmacy. 2, 1601 -1603. 
  • Arawwawala, L.D.A.M., Arambewela, L.S.R., Ratnasooriya, W.D. (2012). Aipinia calcarata Roscoe: A potent antiinflammatory agent. Journal of Ethnopharmacology. 139, 889 – 892. 
  • Lenore, R.D.K., Dharmadasa, R.M., Abesingha, D.C., Arawwawala, L.D.A.M.  (2012). Investigation of plumbagin content in Plumbago indica Linn. Pharmacologia. 3, 57-60.
  • Arawwawala, L.D.A.M.,Arambewela, L.S.R., Ratnasooriya, W.D. (2012).  Alpinia calcarata Roscoe: A rich source of phytopharmaceuticals in Sri Lnaka. The Natural Products Journal.2, 263 -267.
  • Arawwawala, L.D.A.M., Thabrew, I., Arambewela, L.S.R. (2012). Lipid lowering effect of hot water extract of  Trichosanthes cucumerina Linn and antihyperglycemic activity of its fractions on streptozotocin- induced diabetic rats. Israel Journal of Plant Sciences. 60, 447 – 455.
  • Arawwawala, L.D.A.M., W.A. N. Wickramaarachchi., (2012). Berberine content in Coscinium fenestratum (Gaertn.) Colebr grown in Sri Lanka. Pharmacologia. 3,679 – 682.
  • Arawwawala, L.D.AM., Thabrew, M.I., Arambewela, L.S.R. (2013). A review of the pharmacological properties of Trichosanthes cucumerina Linn of Sri Lankan origin. Unique Journal of Pharmaceutical and Biological Sciences. 1, 3-6.
  • Arawwawala, L.D.AM., Thabrew, M.I., Arambewela, L.S.R. (2013).   Trichosanthes   cucumerina Linn: Investigations of some selected  pharmacological activities of ethanolic extract. Pharmacologia. 4, 493 – 494.
  • Hewageeganage, H.G.S.P., Arawwawala, L.D.A.M. (2013). Phytochemical and              Anti oxidant activity of Traditional Decoction used for Type 2 Diabetes Mellites. Universal Journal of Pharmacy. 2, 134-137.
  • Hewageegana, H.G.S.P., Arawwawala, L.D.A.M., Fernando, P.I.P.K., Dhammarathana, I., Ariyawansa, H.A.S., Tissera, M.H.A., (2013). Standardization of Vipadikahara grita taila: An Ayurvedia medicated ouil for common skin diseases. Unique Journal of Ayurvedic and Herbal Medicines. 1, 48-51.
  • Hewageegana, S., Arawwawala, M., Fernando, P, Dhammarathana, I., Ariyawansa, S (2014). A comparative study of physico-chemical and phytochemical parameters: glands/hairs of the fruits and the leaves of Mallotus philipinensis (Lam.) Muell. Arg.  grown in Sri Lanka. Journal of the National Science Foundation. 42, 291 -295.
  • Arawwawala, L.D.A.M., Arambewela, L.S.R. & Ratnasooriya, W.D. (2014).     Gastroprotective effect of Piper betle grown in Sri Lanka.  Journal of Ayurveda & Integrative Medicine. 5, 38 – 42. 
  • Hewageegana, S., Arawwawala, M., Fernando, P., Dhammarathana, I., Ariyawansa, S. (2014). Standardization of a substitute oil for Vipadikahara grita taila which used for skin diseases. Pharmacologia. 32-35.
  • Hewageegana, S., Arawwawala, M.,  Dhammarathana, I., Ariyawansa, S. (2014). Standardization of Sri Lankan market samples of Rubia cordifolia Linn. Journal of Pharmacognosy and Phytochemistry. 3, 122-126.
  • Hewageegana, S., Arawwawala, M.,  Dhammarathana, I., Ariyawansa, S.,  Tissera, M.H.A. (2014). Proximate  analysis and   standardization of leaves of  Leptadenia reticulate (Retz) Wight And Arn. (Jeevanti). World Journal of Pharmaceutical Research.3, 1603-1612.

 

Monographs/Book Chapters

 

  • Hewageegana, H.G.S.P., Arawwawala, L.D.A.M., Arambewela, L.S.R., Ariyawansa, H.S. (2012). Traditional Treatments in Sri Lanka for Madumeha“Diabetes Mellitus”. Publication of Department of Ayurveda, Sri Lanka.
  • Arawwawala, L.D.A.M., Thabrew, I., Arambewela, L.S.R. (2012). A review of pharmacognostical, pharmacological and toxicological investigations of Trichosanthes cucumerina Linn of Sri Lankan origin. In: Ethnomedicine and Therapeutic Validation. RPMP Vol 32, USA.

 

 Communications :International Symposia

  • Arambewela, L.S.R., S, Perera., Arawwawala, L.D.A.M., P, Dissanayake., (2001). Quality control of Ayurvedic Medicines Produced in Ritigala Area, Sri Lanka. Proceedings of the Regional workshop held at Pakhara, Nepal. pp 1
  • Arambewela. L.S.R., Arawwawala, L.D.A.M., Ratnassoriya, W.D., (2004). Hypoglycaemic activities of Alpinia calcarata extracts. NFASSA Regional Symposium on Natural Products. p 27.
  • Arambewela. L.S.R., Arawwawala, L.D.A.M., Ratnassoriya, W.D., (2005). Gastroprotective, Antioxidant and Toxicological studies on Alpinia calcarata. International Symposium on Herbal Medicines, Phytopharmaceutical and other Natural Products. p 44.
  • Arambewela. L.S.R., Arawwawala, L.D.A.M., Ratnassoriya, W.D., (2005). Piper betle: A remedy for diabetes. International Symposium on Herbal Medicines, Phytopharmaceutical and other Natural Products. p 54.
  • Arawwawla, L.D.A.M., Arambewela, L.S.R., Thabrew, M.I., Rokeya, B., Ali, M (2007). Experimental evaluation of the antidiabetic activity of Trichosanthes cucumerina. Svastha International Ayurveda Conference, UK.
  • Arawwawla, L.D.A.M., Arambewela, L.S.R., Thabrew., 2007. Hypoglycemic activity of Trichosanthes cucumerina. International Conference, CHEMTECH, Institute of Chemistry 2007, Sri Lanka. P. 43
  • Arawwawala, L.D.A.M., Thabrew, M.I., Arambewela, L.S.R., 2008. Antioxidant activity of Trichosanthes cucumerina: in vivo investigation. International symposium on Innovation in Food Science and Technology and Health – care for Social Well –being, Institute of Chemistry, Sri Lanka.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M.., Ratnasooriya, W.D., 2008. Bioactivities of Alpinia calcarata. International Seminar on Medicinal Plants and Herbal Products. India.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Kulatunga, W.M.S.S.K.I., Vithanage, D.K.,  2009. Efficacy of betel cream on skin diseases (Kushta roga). 3rd International Conference on Ayurveda and complementary System of Medicine. Organized by Ayurveda Research Foundation, Pune, (India).
  • Hewageegana, H.G.S.P., Arawwawala, L.D.AM. (2011). Kumbukpotuadhi Decoction: A preliminary study on antioxidant activity and phytochemicals. 3rd International Conference on Medicinal Plants and Herbal Products. p. 106.
  • Arambewela, L.S.R., Arawwawala, L.D.A.M., Kumaratunga, K.G.A., Dissanayake, D.S.C.T., Ratnasooriya, W.D., Kumarasingha, S.P.W. (2011). Piper betle Linn: A potential candidate for new drug development and commercial exploitation. 3rd International Conference on Medicinal Plants and Herbal Products. p. 55.
  • Lenore, R.D.K., Dharmadasa, R.M., Arawwawala, L.D.A.M., Abesingha, D.C. (2011). Comparison of antioxidant and cytotoxic properties of Plumbago indica Linn. grown under different growing systems. 3rd International Conference on Medicinal Plants and Herbal Products. p. 107.
  • Arawwawala, L.D.A.M., Thabrew, M.I., Arambewela, L.S.R., Handunnetti, S. (2012). Trichosanthescucumerina Linn: As a potent anti-inflammatory agent. International Conference of Chemical Sciences. Colombo, Sri Lanka, June 22. pp.24
  • Hewageegana, S., Arawwawala, M.,  Tissera, A., Dammaratana, I. (2012). Physico-chemical and Phytochemical evaluation of fruit powder and Leaves of Mallotusphilippinesis (Lam.) Muellgrown in Sri Lanka, Pandit G.P Wicramarachchi Memorial International Research Symposium. Colombo, Sri Lanka, November 7.pp 52
  • Hewageegana,  S.,  Arawwawala,  M., Tissera, A., Dammaratana, I. (2012).  A Comparative Phytochemical and Physicochemical Evaluation: Tiktaanguna, Kirianguna and Jeewanti, International Conference on Holistic medicine. Colombo, Sri Lanka, November 17. pp.47.
  • Arawwawala, L.D.A.M., Wickramaarachchi, W.A.N. (2013). Quantification of berberine in methanolic extracts of Coscinium fenestratum (Gaertn.) Colebr grown in Sri Lanka. International Conference on Unani, Ayurveda, Siddha and Traditional Medicine.
  • Hewageegana, H. G. S. P., Arawwawala, L. A. D. M., Kottahachchi, J., Athukorala, G.I.D.D.A.D,, Weerasekera, M. M.,  Gunasekera, T. D. C. P., Dissanayaka, D. M. D. T.,  Basnayake, P., Dhammarathana, I.,  Ariyawansa, H, A, S., Tissera, M, H, A., Fernando, S. S. N. (2013). Berberies ceylanica Schneider: Antimicrobial activity and quantification of berberine content. International Conference on Unani, Ayurveda, Siddha and Traditional Medicine. 75
  • Hewageegana, H. G. S. P., Arawwawala, L. A. D. M., Fernando, P.I.P.K.,  Kottahachchi, J., Athukorala, G.I.D.D.A.D,, Weerasekera, M. M.,  Gunasekera, T. D. C. P., Dissanayaka, D. M. D. T.,  Basnayake, P., Dhammarathana, I.,  Ariyawansa, H, A, S., Tissera, M, H, A., Fernando, S. S. N. (2013). Standardization and Evaluation of the Antibacterial activity of Vipadikahara gritataila. International Conference on Unani, Ayurveda, Siddha and Traditional Medicine. 34.
  • Nazeem, R., Mawjood, A.H.M., Arawwawala, L.D.A.M. (2013). Physico-chemical, phytochemical and antioxidant properties of popular blood purifier drug “Glinus oppositifolius” grown in Sri Lanka. Conference on Unani, Ayurveda, Siddha and Traditional Medicine. 32.
  • Arawwawala, L.D.AM., Thabrew, M.I., Arambewela, L.S.R. (2013). An investigation of Therapeutic properties of Trichosanthes cucumerina Linn of Sri Lankan Origin. World Congress on Pharmaceutical Sciences & Chemical Technology. P.77.  
  • Arawwawala, L.D.A.M., Karunakaran, R., Thammitiyagodage, M.G., Thabrew, M.I. Investigation of total polyphenolic content and flavonoid content in fractions of Trichosanthes cucumerina hot water extract. Proceedings of 2nd International Conference on Ayurveda, Unani, Siddha & Traditional Medicine. p.158
  • Pallie, M.S., P.K. Perera., Arawwawala, M., Goonasekara, C.L., Kumarasingha, K.M.N. (2014).  Fagonia cretica - A Literary Study. Proceedings of 2nd International Conference on Ayurveda, Unani, Siddha & Traditional Medicine. p.73.
  • Pallie, M.S., P.K. Perera., Arawwawala, M., Goonasekara, C.L., Kumarasingha, K.M.N. (2014). A comprehensive review on Tragia  involucrate. Proceedings of 2nd International Conference on Ayurveda, Unani, Siddha & Traditional Medicine. p.74.
  • Hewageegana, S., Arawwawala, M.,  Dhammarathana, I., Ariyawansa, S., Tissera, M.H.A. (2014). Proximate  analysis, antioxidant activity and   standardization of leaves of  Leptadenia reticulate (Retz) Wight And Arn. (Jeevanti). Proceedings of 2nd International Conference on Ayurveda, Unani, Siddha & Traditional Medicine. p.128.  

 

 

 

Major Projects Undertaken

  • Comparative clinical study on the efficacy of Piper betle L hot water extract and Tripala on Diabetes Mellitus
  • Pharmacological and phytochemical studies of Trichosanthes cucumerina
  • Establishment of Quality control and Standardization parameters for Asamodagam spirit              
  • Development of a natural gastroprotective agent from Trichosanthes cucumerina   Linn  
  • Identification of chemical fraction of Tragia involucrata L. and the effect on hyperglycaemic subjects.

Last Updated on Thursday, 17 September 2015 10:14

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